Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene180890921792284018029944179625211796377018005966
Basic Information
VIS ID
TVIS44033368
Fusion event
HTLV-1-PCM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
NCBI36/hg18
Start
17907755/18005966 (Hg38)
End
17907755/18005966 (Hg38)
Orient
-
Location type
Intronic
Target gene
PCM1
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-129-5p ; hsa-mir-8055
Nearest miRNA
hsa-mir-124-1/Upstream/324309; hsa-mir-10400/Downstream/4239000;
Nearest TSS
ENST00000518652/Upstream/25745; ENST00000521338/Downstream/88;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/82203, chr8-CpG: 103/Downstream/77824
Upstream sequence
AATAGGGAATTGGGTACAAGGTGAGTATGCTTGTAAGAGTATTTGAAATTAACTGAATGAAAACAGAAAGATTGGCAAAATGGAAACTAGCATGAATAGT
Downstream sequence
TCTCCTTAAGGTACAGAAAAGTACAGAAAGAAAGTGCTGAAAAGTACTGGATCAGCCAGTTCTTTTACTGGCCATCATCTGCTTTCGTGGGTCAAAATTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate