Basic Information
VIS ID
TVIS44033378
Fusion event
HTLV-1-ZNF25 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p11.21
Reference genome
NCBI36/hg18
Start
38281607/37952673 (Hg38)
End
38281607/37952673 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF25
miRNAs that regulate target gene
hsa-mir-181a-5p ; hsa-mir-489-3p ; hsa-mir-431-5p ; hsa-mir-7976 ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-4732-3p ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-6516-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-153-5p ; hsa-mir-4760-3p ; hsa-mir-4662a-5p
Nearest miRNA
hsa-mir-1265/Upstream/2311421; hsa-mir-107/Downstream/5044890;
Nearest TSS
ENST00000439456/Upstream/94567; ENST00000412789/Downstream/23919;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/94497, chr10-CpG: 56/Downstream/23474
Upstream sequence
GTGACTTCTCTGATGAGTTTTGAGGTGTGAATTCCTAGAGAAGAATTTCCCACATTCCTTACATTTATAGGGTTTCTCCCCTGTGTGCATTCTCTGATGT
Downstream sequence
ACTGTGAGGTGTGACTTCTGGGAAAAGGCTTTCCCACACTCCTTACACTCATAGGGTTTCTCCCCTGTGTGTGTTTTCTGATGTACCATGAGGTATGCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate