Basic Information
VIS ID
TVIS44033381
Fusion event
HTLV-1-ANKRD44 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
NCBI36/hg18
Start
197579427/197006458 (Hg38)
End
197579427/197006458 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKRD44
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1277-5p ; hsa-mir-4789-5p ; hsa-mir-190a-3p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3171 ; hsa-mir-380-3p ; hsa-mir-383-5p ; hsa-mir-5096 ; hsa-mir-6513-3p ; hsa-mir-129-5p ; hsa-mir-7158-3p ; hsa-mir-4502
Nearest miRNA
hsa-mir-10b/Upstream/7873347; hsa-mir-1244-1/Downstream/9776776;
Nearest TSS
ENST00000437798/Upstream/12820; ENST00000449346/Downstream/82417;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/79175, chr2-CpG: 31/Downstream/157886
Upstream sequence
ggcgtgaacctgggaggcagagcttgcagtgagcccacattgcgccactgcactacggcctgggcgacagagcaagactccatctcaaaaagaaagaaag
Downstream sequence
aaagatatcatgatgcagcagtaaacatgagttttagaatcaggaagatctaagtgaaatcttggcacccctgtgacaggtcagttcgcctctccatccc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate