Basic Information
VIS ID
TVIS44033404
Fusion event
HTLV-1-BCL7B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
72593900/73541634 (Hg38)
End
72593900/73541634 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
BCL7B
miRNAs that regulate target gene
hsa-mir-106b-3p ; hsa-mir-23b-3p ; hsa-mir-4656 ; hsa-mir-6810-5p ; hsa-mir-1226-5p ; hsa-mir-6867-5p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-4451 ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-6721-5p ; hsa-mir-92b-5p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-7854-3p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-4520-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-4446-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-576-3p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1287-5p ; hsa-mir-1-3p ; hsa-mir-206 ; hsa-mir-3135b ; hsa-mir-6128 ; hsa-mir-613
Nearest miRNA
hsa-mir-1183/Upstream/843656; hsa-mir-10399/Downstream/169683;
Nearest TSS
ENST00000635602/Upstream/1066; ENST00000324941/Downstream/1967;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/18874, chr7-CpG: 69/Downstream/15596
Upstream sequence
tcagctcaccacaacctctgcctcctgggttcaactgattctcctgcctcagcctcttgagtagctgggattacaggcttgcgccaccacgcctgggtaa
Downstream sequence
ttttgtatttttattagagacggggtttcaccatgttggtcaggctggtctcgaactcctgacctcaggtaatccacctgcctcagcctcccaaagtgct
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate