Basic Information
VIS ID
TVIS44033411
Fusion event
HTLV-1-SLC24A3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
NCBI36/hg18
Start
19154660/19226016 (Hg38)
End
19154660/19226016 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
SLC24A3
miRNAs that regulate target gene
hsa-let-7c-3p ; hsa-mir-3177-5p ; hsa-mir-4475 ; hsa-mir-4668-5p ; hsa-mir-511-3p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548t-3p ; hsa-mir-5584-5p ; hsa-mir-624-3p ; hsa-mir-7845-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/755325; hsa-mir-1-1/Downstream/6982170;
Nearest TSS
ENST00000382410/Upstream/12539; ENST00000432334/Downstream/58580;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/12758, chr20-CpG: 127/Downstream/531379
Upstream sequence
ttcctttttcttgacttattacagtggctaagacttttagtacaatattgagtttgaatggacatccttgtcttgtgtccctgatattagggggaaaacg
Downstream sequence
tttagtccttccctgttaagtatgctatttgctgtaggtttttcatagattgcctttatcaaattgagtaatttcctttttcgccttagttttctgagag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate