Basic Information
VIS ID
TVIS44033417
Fusion event
HTLV-1-ACBD5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
NCBI36/hg18
Start
27526194/27197259 (Hg38)
End
27526194/27197259 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACBD5
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-5010-3p ; hsa-mir-548aw ; hsa-mir-4671-3p ; hsa-mir-223-5p ; hsa-mir-6073 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-511-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-1277-5p ; hsa-mir-142-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-3668 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4540 ; hsa-mir-6723-5p ; hsa-mir-545-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-5697 ; hsa-mir-4272 ; hsa-mir-6838-3p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-1273e ; hsa-mir-3190-3p ; hsa-mir-3689d ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-495-5p ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-122-3p
Nearest miRNA
hsa-mir-1265/Upstream/2921478; hsa-mir-107/Downstream/1091999;
Nearest TSS
ENST00000439456/Upstream/27315; ENST00000574842/Downstream/43299;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/41694, chr10-CpG: 70/Downstream/43030
Upstream sequence
CCTTCAAGTTCAAGGGCAGGGTAAATCTGTGTATACTACTTATAACCTAGTAGAGATTGATTATTCAAGTATCAGCAATATTAGTCCTTAAAATGTTATC
Downstream sequence
GTTTGTGTAGTGCAAAATATATATGTGTATATATGTACACAAACTAAACTACTGGACAACAAAAAGCAATGTAATCATCACAAACTAAGATTTTCTTGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate