Basic Information
VIS ID
TVIS44033429
Fusion event
HTLV-1-STXBP4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
NCBI36/hg18
Start
50543112/55110752 (Hg38)
End
50543112/55110752 (Hg38)
Orient
+
Location type
Intronic
Target gene
STXBP4
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-324-5p ; hsa-mir-7702 ; hsa-mir-151a-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-4448 ; hsa-mir-3670 ; hsa-mir-556-5p
Nearest miRNA
hsa-mir-10226/Upstream/4342022; hsa-mir-1250/Downstream/1780518;
Nearest TSS
ENST00000595228/Upstream/79945; ENST00000572234/Downstream/154260;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/141745, chr17-CpG: 65/Downstream/127505
Upstream sequence
tgttgtaactattcaactctgccattgtagcatgaaagcagccatagataataagtaaacaaaggtgtagtgttccaataaaactttgattctaagaata
Downstream sequence
ggcggcagtccagatttggcccatggctatagtttTTTCAAGTCCTAGCCTAGCACATAAATAATATTTTTAAAAGTAATGGTAAATAAGTCAGGACTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate