Basic Information
VIS ID
TVIS44033467
Fusion event
HTLV-1-FAM76A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
NCBI36/hg18
Start
27940688/27741590 (Hg38)
End
27940688/27741590 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
FAM76A
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-124-3p ; hsa-mir-410-3p ; hsa-mir-3689a-5p ; hsa-mir-3689b-5p ; hsa-mir-3689e ; hsa-mir-3689f ; hsa-mir-5011-5p ; hsa-mir-548g-3p ; hsa-mir-155-5p ; hsa-mir-365b-3p ; hsa-mir-365a-3p
Nearest miRNA
hsa-mir-12136/Upstream/1186997; hsa-mir-101-1/Downstream/2997566;
Nearest TSS
ENST00000473358/Upstream/15533; ENST00000446647/Downstream/3184;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/15099, chr1-CpG: 39/Downstream/31527
Upstream sequence
ATTAAGGTTACAAACAGAAATGTGTCTTAATGCCTAAGGAGGGCATATTAGCTACACTATAAAAAAAATTTTTTTTCCATTTTACAGTAGAGAGAAATAG
Downstream sequence
AAAAACAggccaggcaacggtggcttacacctgtaatcccagcactttgaaaggccaaggtgggtggatcacctgaggtcaggagtttgagaccagcctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate