Basic Information
VIS ID
TVIS44033471
Fusion event
HTLV-1-KDM4C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
NCBI36/hg18
Start
6950679/6960679 (Hg38)
End
6950679/6960679 (Hg38)
Orient
+
Location type
Intronic
Target gene
KDM4C
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-409-3p ; hsa-mir-432-5p
Nearest miRNA
hsa-mir-101-2/Upstream/952775; hsa-let-7a-1/Downstream/11612627;
Nearest TSS
ENST00000422679/Upstream/35178; ENST00000494570/Downstream/23602;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/201807, chr9-CpG: 43/Downstream/838676
Nearest cancer related gene
KDM4C(OG, No orient, 0)
Upstream sequence
AGATTGTCATAGAAAGTAGGAAAAAAGGAAGTTCTTTAAAGAGTGTCGTAGGGAGAAAGATGGTTTAAAGATGATTTCACACTGACACAAATTTTCATGT
Downstream sequence
ACATGTGTATCCATTTGTCCCATATCTGAATGCCCACCCTTTGTAGGCAGTAAACAGTCTCTTTCTCCAAGTTGCTTAGACCCAGTGCAGACATTCTCAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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