Basic Information
VIS ID
TVIS44033477
Fusion event
HTLV-1-TIFA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
NCBI36/hg18
Start
113419057/112278452 (Hg38)
End
113419057/112278452 (Hg38)
Orient
+
Location type
Intronic
Target gene
TIFA
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1273e ; hsa-mir-921 ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4537 ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4257 ; hsa-mir-1247-3p ; hsa-mir-3174 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-302f ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-940
Nearest miRNA
hsa-mir-12113/Upstream/1417805; hsa-mir-1243/Downstream/369422;
Nearest TSS
ENST00000502981/Upstream/5136; ENST00000514594/Downstream/3321;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/45952, chr4-CpG: 50/Downstream/7224
Upstream sequence
GGTAAACCGTCATCTGGAGACAAGTTACTGTCTCTTCTGTGTCAGCATCTTCAAAACTGGTCATGATGTGCACAAGGCCCACCTGCAATAATTAAATTAC
Downstream sequence
CATGTTAGTTTCTGCTTATGCTTGAGGCATTGAGAACTTTGATTCTAACGTTTTGATGAACATCATCTGATAGGCAATTTATCTGGACTTTAAGAAAACA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate