Basic Information
VIS ID
TVIS44033497
Fusion event
HTLV-1-LONP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
46892008/48300596 (Hg38)
End
46892008/48300596 (Hg38)
Orient
-
Location type
Intronic
Target gene
LONP2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-505-5p ; hsa-mir-30c-2-3p ; hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-3692-5p ; hsa-mir-22-3p ; hsa-mir-1182 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-1915-3p ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4639-3p ; hsa-mir-6764-5p ; hsa-mir-6794-3p ; hsa-mir-6864-3p ; hsa-mir-8055
Nearest miRNA
hsa-mir-1225/Upstream/14136923; hsa-mir-11401/Downstream/1992020;
Nearest TSS
ENST00000527434/Upstream/37820; ENST00000564259/Downstream/33716;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/55852, chr16-CpG: 30/Downstream/65223
Upstream sequence
ATCCATTGCATCATCCAGCAAGTCATGTCAGGCTGCCAAGCTCTCCTCTTGCGGCCCTTTTCTAGTAACTACTGTTTTTAAGAGATTTGAAGTATCTCTC
Downstream sequence
TATTTTGAACTTTGACTTAGAGTTTGGCCAGACTGTCTTTTGATCTATGCCTTCTTATGGATCTATTTAGATTTATATACAAAGCAGTAAGACTAAGTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate