Basic Information
VIS ID
TVIS44033498
Fusion event
HTLV-1-TRPM3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q21.12
Reference genome
NCBI36/hg18
Start
72758184/70953448 (Hg38)
End
72758184/70953448 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRPM3
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-4433b-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-6778-3p ; hsa-mir-532-3p ; hsa-mir-1281 ; hsa-mir-1224-3p ; hsa-mir-6814-5p ; hsa-mir-4761-5p
Nearest miRNA
hsa-mir-101-2/Upstream/143364; hsa-let-7a-1/Downstream/13016300;
Nearest TSS
ENST00000422679/Upstream/84390; ENST00000473252/Downstream/168150;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/533139, chr9-CpG: 50/Downstream/493149
Upstream sequence
AGCCTTAGGGGAAGATTACTGTGGGTAATATATTTCTGCTGGTCTCAAACAAACAAACAAAAAGAAAAATAAATACAGTTAAAGTAAGGACATGACATCA
Downstream sequence
TTTTCTGAAAAATGTGACATTGTCTTGCGTTTTTAAATGTCTCCTGAGCACACACTCTTTTTGGAAACCAAAAAATATAATTTTTGAGAAACTTGATTAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate