Basic Information
VIS ID
TVIS44033503
Fusion event
HTLV-1-DLGAP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
NCBI36/hg18
Start
1421694/1486121 (Hg38)
End
1421694/1486121 (Hg38)
Orient
+
Location type
Intronic
Target gene
DLGAP2
miRNAs that regulate target gene
hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-20a-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4764-5p ; hsa-mir-627-3p ; hsa-mir-4635
Nearest miRNA
hsa-mir-10400/Downstream/315004;
Nearest TSS
ENST00000518652/Upstream/108254; ENST00000522499/Downstream/15245;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2963, chr8-CpG: 25/Downstream/6374
Upstream sequence
atctcaaaaaaTTATAATAATTTTAAAAAGGAAGATCAGTCATCAGCATGGTCTTCAAGATCTCTGCTCGCGTCCCgtgctctgccaagatgctgcatgg
Downstream sequence
acatgtttctcacctcatcttcagaaccacccttggcacaaacagcatgatgaccatcctacagataaggaaaccaaggctttcattacttgccccagat
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate