Basic Information
VIS ID
TVIS44033511
Fusion event
HTLV-1-DMRT2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
NCBI36/hg18
Start
1015659/1025659 (Hg38)
End
1015659/1025659 (Hg38)
Orient
+
Location type
Intronic
Target gene
DMRT2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-580-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-646 ; hsa-mir-6501-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-218-1-3p ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-1273e ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-203a-5p ; hsa-mir-876-3p ; hsa-mir-323a-5p ; hsa-mir-4675 ; hsa-mir-4741 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6829-5p ; hsa-mir-5787 ; hsa-mir-4656 ; hsa-mir-4505 ; hsa-mir-4731-5p ; hsa-mir-378g ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-4317 ; hsa-mir-5006-5p ; hsa-mir-7159-5p ; hsa-mir-505-3p ; hsa-mir-1289 ; hsa-mir-4755-3p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-3065-5p
Nearest miRNA
hsa-mir-1302-9/Upstream/995378; hsa-let-7a-1/Downstream/3824638;
Nearest TSS
ENST00000422679/Upstream/35822; ENST00000625222/Downstream/19966;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/26625, chr9-CpG: 60/Downstream/16758
Upstream sequence
TGGCTTTTGGGGAGAATAAAAGCCCAATTACTTCCTTAAAAAAACAAGTGGGCAACTAGATTATTACCTCTTATTTCTGATTTTGAAGAAGAGGAGGTAG
Downstream sequence
GTATAAGCAGTTTGTGTCTGGGAAAGACTAGGGTATACAGACCTCATATAGGCAAAACCATGAGGTCATCAAAATGTGTCACCTGGGCCCTGACTCTAAC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate