Basic Information
VIS ID
TVIS44033513
Fusion event
HTLV-1-SCMH1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
NCBI36/hg18
Start
41334875/41096616 (Hg38)
End
41334875/41096616 (Hg38)
Orient
+
Location type
Intronic
Target gene
SCMH1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-532-3p ; hsa-mir-10b-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-12136/Upstream/339244; hsa-mir-101-1/Downstream/2075036;
Nearest TSS
ENST00000473358/Upstream/25985; ENST00000422305/Downstream/56058;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/78595, chr1-CpG: 155/Downstream/144669
Upstream sequence
accttagccttgttCTCATCTGACTGTAGTGAACTTTCTGCTACTATGTTGCTACGTGGGAGGTGAAGAGCAGGGTAGATTGGAGAGGAAAAGAAATAAA
Downstream sequence
ACACTCATCAGGCAACTACGGCAAAATGATACTCTTGACCCTAATTGTTCTGGGACCCTGAAACTCTGCTCCTGTAGAGGATACAGTCAAAGGGAATCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate