Basic Information
VIS ID
TVIS44033514
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
NCBI36/hg18
Start
84383627/84145356 (Hg38)
End
84383627/84145356 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LOC107985046 ; PRKACB
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-203a-3p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520f-3p ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-513a-3p ; hsa-mir-636 ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-302e ; hsa-mir-513c-3p ; hsa-mir-548x-5p ; hsa-mir-3606-3p ; hsa-mir-3622a-3p ; hsa-mir-3622b-3p ; hsa-mir-1273e ; hsa-mir-3660 ; hsa-mir-548aj-5p ; hsa-mir-4526 ; hsa-mir-548aw ; hsa-mir-3692-3p ; hsa-mir-7158-3p ; hsa-mir-1468-3p ; hsa-mir-2277-3p ; hsa-mir-4539 ; hsa-mir-4724-5p ; hsa-mir-3120-3p
Nearest miRNA
hsa-mir-101-1/Upstream/7085154; hsa-mir-11399/Downstream/988438;
Nearest TSS
ENST00000473358/Upstream/1034; ENST00000467507/Downstream/18961;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/66778, chr1-CpG: 77/Downstream/153069
Upstream sequence
AATTGCACATATAAACAATACTAGTGCCGCCATTCTACATCTCACCTTGGACCCTCCTCAAGGTATTTCTGTGACTCCAATTAGAGGAACAATAGAATTA
Downstream sequence
CCCTTGAAACTTTTGCCCTCTTTGGTGTGTTTGTTTGATCATCAAATAGCACTAGCGTTTGACTCTTTCTGTTTATGTATTTGGTAGCAGTTAAGGAAGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate