Basic Information
VIS ID
TVIS44033520
Fusion event
HTLV-1-KCTD5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
NCBI36/hg18
Start
2696214/2706212 (Hg38)
End
2696214/2706212 (Hg38)
Orient
+
Location type
Intronic
Target gene
KCTD5
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-125a-3p ; hsa-mir-134-5p ; hsa-mir-155-5p ; hsa-mir-583 ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-3118 ; hsa-mir-3128 ; hsa-mir-3605-5p ; hsa-mir-6894-5p ; hsa-mir-4470 ; hsa-mir-3135a ; hsa-mir-873-5p ; hsa-mir-6089 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-34a-3p ; hsa-mir-5008-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3194-3p ; hsa-mir-3607-3p ; hsa-mir-3686 ; hsa-mir-5096 ; hsa-mir-5691 ; hsa-mir-6767-5p ; hsa-mir-6805-3p ; hsa-mir-7974
Nearest miRNA
hsa-mir-1225/Upstream/174207; hsa-mir-11401/Downstream/779169;
Nearest TSS
ENST00000527434/Upstream/20598; ENST00000574340/Downstream/9353;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/9102, chr16-CpG: 30/Downstream/1322
Upstream sequence
AGAGTGAGTGGGAGCCTCGAGCTAGAAGTGGTCCAGGGCACTGAGCCTGGGGGGCACCCGCCTGGGAACGGCAGAGCTGTTGGGGGGTGGAGTATTGGAG
Downstream sequence
TCAGGCTGAGCAGCTCAGGGGACGTGGCCTCCAGGAGCCTTCGGAACAAGCCTGGGGTGGCATGCACCTCTCACCACTGCCCTCTCTCCGGTCAGTGCGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate