Basic Information
VIS ID
TVIS44033528
Fusion event
HTLV-1-CADM2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p12.1
Reference genome
NCBI36/hg18
Start
85685165/85553325 (Hg38)
End
85685165/85553325 (Hg38)
Orient
+
Location type
Intronic
Target gene
CADM2
miRNAs that regulate target gene
hsa-mir-624-3p ; hsa-mir-1277-5p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-410-3p ; hsa-mir-1273e ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4766-5p ; hsa-mir-6074 ; hsa-mir-4778-5p ; hsa-mir-512-3p ; hsa-mir-888-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-106b-5p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520e ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302e ; hsa-mir-520d-3p ; hsa-mir-302a-3p ; hsa-mir-302d-3p ; hsa-mir-5704 ; hsa-mir-4529-5p ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-489-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-203a-3p ; hsa-mir-627-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-195-3p
Nearest miRNA
hsa-let-7g/Upstream/167533; hsa-mir-12124/Downstream/1672864;
Nearest TSS
ENST00000440867/Upstream/593779; ENST00000405615/Downstream/173157;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/593639, chr3-CpG: 78/Downstream/1437135
Nearest cancer related gene
CADM2(TSG, No orient, 0)
Upstream sequence
GATGATAATGATGATGATGCCTGCttaccaagcatctaccatatatcaggtactctagatctagtttattgtgttttatttcttttttttaaacaaagaa
Downstream sequence
gatactattcttaattgtatacaagaagcagctgagcttccagaaatgtaactttcccaatgatacataattgctaaCTTCTACAAGCACAGGCTAATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate