Basic Information
VIS ID
TVIS44033532
Fusion event
HTLV-1-RAD51B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
68185038/68648568 (Hg38)
End
68185038/68648568 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
RAD51B
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-2053 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-30b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-569 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-6871-5p ; hsa-mir-4496 ; hsa-mir-4506
Nearest miRNA
hsa-mir-208a/Upstream/1206638; hsa-mir-1185-1/Downstream/3868252;
Nearest TSS
ENST00000550708/Upstream/20123; ENST00000553944/Downstream/36997;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/19878, chr14-CpG: 34/Downstream/141391
Upstream sequence
CACCCTACTTTGGAGACCAGCCATATAAAAGCTAAGTATTAGTGGGATATTTGTGAGTTCATTCTGCCTGGGGCACATACAGAATTCTGTGCAACATCTG
Downstream sequence
CACACTCATTTGAATTTAAATGTACAGAATTCAAAATGCCCTCTGAAGCTTAACGAAGAATTTTTAAACTAGTGGGACAAAGCTCAATAATGGTAAAAGc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate