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TVIS44033535
Basic Information
VIS ID
TVIS44033535
Fusion event
HTLV-1-MAP3K2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
NCBI36/hg18
Start
127850700/127376654 (Hg38)
End
127850700/127376654 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
MAP3K2
miRNAs that regulate target gene
hsa-mir-26a-5p
;
hsa-mir-520b
;
hsa-mir-21-5p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-125b-5p
;
hsa-mir-221-3p
;
hsa-mir-5094
;
hsa-mir-579-3p
;
hsa-mir-664b-3p
;
hsa-mir-129-5p
;
hsa-mir-6782-3p
;
hsa-mir-8063
;
hsa-mir-4778-3p
;
hsa-mir-6875-3p
;
hsa-mir-106b-5p
;
hsa-mir-20a-5p
;
hsa-mir-549a
;
hsa-mir-330-3p
;
hsa-let-7c-3p
;
hsa-mir-5587-5p
;
hsa-mir-3177-5p
;
hsa-mir-6801-5p
;
hsa-mir-4302
;
hsa-mir-6733-3p
;
hsa-mir-759
;
hsa-mir-5585-3p
;
hsa-mir-6866-5p
;
hsa-mir-4451
;
hsa-mir-920
;
hsa-mir-6726-5p
;
hsa-mir-5591-5p
;
hsa-mir-4300
;
hsa-mir-6090
;
hsa-mir-6827-5p
;
hsa-mir-6500-5p
;
hsa-mir-4633-3p
;
hsa-mir-6770-5p
;
hsa-mir-4756-3p
;
hsa-mir-3919
;
hsa-mir-6871-5p
;
hsa-mir-196b-5p
;
hsa-mir-196a-5p
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-5582-5p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-526b-3p
;
hsa-mir-106a-5p
;
hsa-mir-455-3p
;
hsa-mir-452-3p
;
hsa-mir-4511
;
hsa-mir-548b-3p
;
hsa-mir-3140-3p
;
hsa-mir-6738-3p
;
hsa-mir-544a
;
hsa-mir-5001-3p
;
hsa-mir-4727-5p
;
hsa-mir-5696
;
hsa-mir-3978
;
hsa-mir-5093
;
hsa-mir-6817-5p
;
hsa-mir-4769-3p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-190b
;
hsa-mir-190a-5p
;
hsa-mir-3679-3p
;
hsa-mir-6868-3p
;
hsa-mir-6826-3p
;
hsa-mir-1248
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-5088-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-520a-3p
;
hsa-mir-186-5p
;
hsa-mir-1257
;
hsa-mir-143-5p
;
hsa-mir-329-5p
;
hsa-mir-4455
;
hsa-mir-4503
;
hsa-mir-574-5p
;
hsa-mir-6792-5p
;
hsa-mir-6867-5p
;
hsa-mir-7856-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/13655286; hsa-mir-10b/Downstream/46883;
Nearest TSS
ENST00000437798/Upstream/33425;
ENST00000433673/Downstream/11278;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/82373
,
chr2-CpG: 116/Downstream/10629
Upstream sequence
gggttggacccagcagttccgtacaggggctgctcccatgtgaggtcccaaagtgggacccaaagtaaggatgacaaaaatgttgagctgagcccccagc
Downstream sequence
tgaccctcaatgaatacatggtatgagcaaaacatacaccttctgttgttttaagccactgagatattggggtttttgttCACAGCCTACTCAGAATAAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Sample Information
×
Sample name
Co15
Sample type
Nontumor
Age
64
Gender
Male
CpG Island Information
×
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