Basic Information
VIS ID
TVIS44033561
Fusion event
HTLV-1-COL14A1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
NCBI36/hg18
Start
121402801/120321381 (Hg38)
End
121402801/120321381 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
COL14A1
miRNAs that regulate target gene
hsa-mir-324-5p ; hsa-mir-210-5p ; hsa-mir-3189-5p ; hsa-mir-4758-3p ; hsa-mir-5699-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-6752-3p ; hsa-mir-7108-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-548an
Nearest miRNA
hsa-mir-12123/Upstream/996116; hsa-mir-10400/Downstream/2894407;
Nearest TSS
ENST00000518652/Upstream/70634; ENST00000440844/Downstream/24065;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/195842, chr8-CpG: 24/Downstream/123732
Upstream sequence
CCTGGGCACATCTGAGAAGAGAACAGCTACTAAAACATATTAGTTTCCTGTTTTTACTGACTCTAGAGATACTTCTGggccaggcacggtggctcacgcc
Downstream sequence
tataatcccagcactttgggaggctgaggcaggtggatcacaaggtcaggcgttcaagacaagcctggccaacatggtgataccccgtccctactaaaaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate