Basic Information
VIS ID
TVIS44033589
Fusion event
HTLV-1-SLC26A7 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
92387934/91306530 (Hg38)
End
92387934/91306530 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC26A7
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-3156-5p ; hsa-mir-409-3p
Nearest miRNA
hsa-mir-12123/Upstream/100971; hsa-mir-10400/Downstream/1723221;
Nearest TSS
ENST00000518652/Upstream/10906; ENST00000517930/Downstream/36500;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/235773, chr8-CpG: 151/Downstream/795298
Upstream sequence
TGAATAGCACACACTTTGGTGAGAAATTTAGACTTACCTGAAGATTCTGTGGAACAGGTGGAGAGGATTTTCTTTTCTTTTTTTCACTTTTAATAACttt
Downstream sequence
cactttaggatgattttagatttgcagaaaagcacaaaaatagtacccagagttgacatataacccacacagtttcccctgttactaacatcttacatta
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate