Basic Information
VIS ID
TVIS44033600
Fusion event
HTLV-1-ANKRD28 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
NCBI36/hg18
Start
15816446/15799935 (Hg38)
End
15816446/15799935 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKRD28
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-21-5p ; hsa-mir-221-3p ; hsa-mir-130b-5p ; hsa-mir-3180-5p ; hsa-mir-513b-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6885-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3617-3p ; hsa-mir-3074-3p ; hsa-mir-3614-3p
Nearest miRNA
hsa-mir-12127/Upstream/102564; hsa-let-7g/Downstream/73836;
Nearest TSS
ENST00000440867/Upstream/1751; ENST00000470031/Downstream/59487;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/197861, chr3-CpG: 142/Downstream/59055
Upstream sequence
ATTGTCTCCTTCCACTTTCTTCCACCTATAAATAATTTCATTGAAATGAATTCTGTCGTCACGAGACTCTGGAAGGGTGGAGATTTATAAACAAGAATAG
Downstream sequence
TGGGGGTGTGTTGGTATACATATATTTTAACCAGAAAATATAGGTGGCATTAAGGTGCAACAAAGTGAGTTTCATATCTCTAATAAGTGAACAATTAAAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate