Basic Information
VIS ID
TVIS44033609
Fusion event
HTLV-1-MMAA integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
NCBI36/hg18
Start
146761930/145621328 (Hg38)
End
146761930/145621328 (Hg38)
Orient
+
Location type
Intronic
Target gene
MMAA
Nearest miRNA
hsa-mir-12113/Upstream/2277793; hsa-mir-1305/Downstream/787255;
Nearest TSS
ENST00000502981/Upstream/2343; ENST00000503730/Downstream/17765;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1824, chr4-CpG: 63/Downstream/111514
Upstream sequence
cccaggttccatagttggtctcagagcttcctagttcaagcctggatttgAAATAGGGTGGTAGCAGTGGGAATCAAAACATTTAATGGTGATGGAATTT
Downstream sequence
AGAAAAATAGAGACTTCTCAAGCACATTTAAGCCTAAAAGTAGGAATTGGGAAATCTGAATCTTACTGGAAAAGTGATAAAAAGTAAAGTGGACAGAGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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