Basic Information
VIS ID
TVIS44033628
Fusion event
HTLV-1-GAL3ST1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
29296002/30570015 (Hg38)
End
29296002/30570015 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22B
Target gene
GAL3ST1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1286/Upstream/562902; hsa-let-7a-3/Downstream/161542;
Nearest TSS
ENST00000624155/Upstream/3854; ENST00000423350/Downstream/2815;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/13927, chr22-CpG: 48/Downstream/4575
Upstream sequence
gtataaaaaatttaaacattagccctgtgtggtggtgcacgcctgtagccccagctactcaggaggctgaggcaagaggaccccttgaacccagaagttc
Downstream sequence
aaggttacagagaggtatgaacgtaccactgcactccaagcctgggcaacagtgtgagaccccatcttaaaaaaagaaactccaagaaacaaaaGCCATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate