Basic Information
VIS ID
TVIS44033629
Fusion event
HTLV-1-FOXP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
NCBI36/hg18
Start
71575394/71443553 (Hg38)
End
71575394/71443553 (Hg38)
Orient
+
Location type
Intronic
Target gene
FOXP1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-335-5p ; hsa-mir-33a-5p ; hsa-mir-22-3p ; hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-9-5p ; hsa-mir-512-5p ; hsa-mir-218-5p ; hsa-mir-4276 ; hsa-mir-105-5p ; hsa-mir-7853-5p ; hsa-mir-578 ; hsa-mir-548aw ; hsa-mir-526b-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1181 ; hsa-mir-5195-5p ; hsa-mir-4480 ; hsa-mir-577 ; hsa-mir-497-3p ; hsa-mir-1277-5p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-let-7c-3p ; hsa-mir-486-5p ; hsa-mir-8485 ; hsa-mir-649 ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6882-3p ; hsa-mir-27b-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-367-5p ; hsa-mir-4639-5p ; hsa-mir-4517 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6507-3p ; hsa-mir-1264 ; hsa-mir-431-5p ; hsa-mir-561-3p ; hsa-mir-6821-5p
Nearest miRNA
hsa-let-7g/Upstream/2394518; hsa-mir-12124/Downstream/98417;
Nearest TSS
ENST00000440867/Upstream/82793; ENST00000615819/Downstream/100004;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/377883, chr3-CpG: 155/Downstream/137869
Nearest cancer related gene
FOXP1(OG, No orient, 0)
Upstream sequence
taactctgGGTTCACGtctgtcggtctaacaagccctccaggtgaccctgatgcacactcgagttggaaagccactgCCTTCTCTCCAtgcttctcaaca
Downstream sequence
gtcatgaccatcagaatcgcctatagggctggttaaaacacagactgccagccctcatgccagattttctgattctgccactctccctccaacagggccc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate