Basic Information
VIS ID
TVIS44033634
Fusion event
HTLV-1-NAV3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
NCBI36/hg18
Start
76806776/77888865 (Hg38)
End
76806776/77888865 (Hg38)
Orient
+
Location type
Intronic
Target gene
NAV3
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-21-5p
Nearest miRNA
hsa-let-7i/Upstream/8304042; hsa-mir-1178/Downstream/1530392;
Nearest TSS
ENST00000382841/Upstream/57576; ENST00000551277/Downstream/51402;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/822703, chr12-CpG: 38/Downstream/915419
Upstream sequence
AGTCACTGAATGTTCTAAGTCTTCAAATGTTTTTATCTTTGTTTTCTCAGAGAGGTGAGTCATATGTGTGTGACTGTGGATAGGACCGGTGTTCTTCTGC
Downstream sequence
TCAATAACATACATACTCAGGGGGAACTCCATCTTGTTCTATATAATATGGACAAGTGATTTCTTGAAAAAAATTTTAGGACAGATTTGGTCAATTGAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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