Basic Information
VIS ID
TVIS44033658
Fusion event
HTLV-1-ZNF33A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p11.1
Reference genome
NCBI36/hg18
Start
38393143/38064209 (Hg38)
End
38393143/38064209 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF33A
miRNAs that regulate target gene
hsa-mir-18a-5p ; hsa-mir-615-3p ; hsa-mir-544b ; hsa-mir-544a ; hsa-mir-541-5p ; hsa-mir-6770-3p ; hsa-mir-4730 ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-4524a-3p ; hsa-mir-219b-3p ; hsa-mir-4329 ; hsa-mir-4768-3p ; hsa-mir-4524b-3p ; hsa-mir-647 ; hsa-mir-3911 ; hsa-mir-4800-5p ; hsa-mir-3138 ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-5580-5p ; hsa-mir-4663 ; hsa-mir-6499-3p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-4487 ; hsa-mir-3160-3p ; hsa-mir-1253 ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-17-3p ; hsa-mir-4649-3p ; hsa-mir-4302 ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-3656
Nearest miRNA
hsa-mir-1265/Upstream/2422957; hsa-mir-107/Downstream/4933354;
Nearest TSS
ENST00000439456/Upstream/53510; ENST00000498773/Downstream/30125;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/53038, chr10-CpG: 63/Downstream/30063
Upstream sequence
TGGATTAAACCCCTGCAGTGCTGGAAGAAGAGGACTCTGCACTGCCTGCCACACCAGGACTGGAAGATCCATGGCCTTCCCTTCTTCCAAACTACCTTCC
Downstream sequence
CACAAGATGGGGATGGTGGTCACATCTCCAACACTAGCATGCTGTGGAAGAGACATCAGCATTCTTGCAACAAATCTGGAAACAGCCTAAAGAGACATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate