Basic Information
VIS ID
TVIS44033686
Fusion event
HTLV-1-TERF1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
NCBI36/hg18
Start
74087724/73012935 (Hg38)
End
74087724/73012935 (Hg38)
Orient
+
Location type
Intronic
Target gene
TERF1
miRNAs that regulate target gene
hsa-mir-346 ; hsa-let-7e-5p ; hsa-mir-155-5p ; hsa-mir-6128 ; hsa-mir-6506-3p ; hsa-mir-6888-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-3120-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-3664-5p ; hsa-mir-508-5p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3612 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4728-5p ; hsa-mir-490-3p ; hsa-mir-558 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7851-3p
Nearest miRNA
hsa-mir-124-1/Upstream/8633678; hsa-mir-10400/Downstream/1535608;
Nearest TSS
ENST00000518652/Upstream/78; ENST00000522018/Downstream/9298;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/3618, chr8-CpG: 89/Downstream/79851
Upstream sequence
gtttaattgtgtcttctcagattaaaaccttcatgggggcagagactggctatctgaagtcatcacctcctaacacaggctggcagtagatgttcagtaa
Downstream sequence
atattgaatgGCTTGTGTTTAAATTCTATATAAATTTTGTGCTCTCTTAAAATCCTGTTAAATTCTATTATGACTGTGTATGGTCCAGATAATCTCTGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate