Basic Information
VIS ID
TVIS44033708
Fusion event
HTLV-1-CYFIP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
NCBI36/hg18
Start
156632366/157272778 (Hg38)
End
156632366/157272778 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYFIP2
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-149-5p ; hsa-mir-9-5p ; hsa-mir-3146 ; hsa-mir-335-3p ; hsa-mir-4729 ; hsa-mir-491-3p ; hsa-mir-5003-3p ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-664b-3p
Nearest miRNA
hsa-mir-10397/Upstream/2443238; hsa-mir-103a-1/Downstream/3201624;
Nearest TSS
ENST00000502646/Upstream/3403; ENST00000518511/Downstream/4281;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/6039, chr5-CpG: 50/Downstream/187183
Upstream sequence
cctgcccccgtctctcaagataggaagagctctattttaacctaaatcaggtttaaagtgtctacattattaatatatataaatgatgatcacagacagc
Downstream sequence
caagtaaagtcctttgattatatttcctttcttagagggcttttcatttCGCTGCAGAATTTTTGTTGCAATACTTGTCTTtttatttatctatttattt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate