Basic Information
VIS ID
TVIS44033710
Fusion event
HTLV-1-EPHA5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
66012541/65464228 (Hg38)
End
66012541/65464228 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPHA5
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-181a-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p
Nearest miRNA
hsa-mir-12113/Upstream/4541544; hsa-mir-1243/Downstream/812596;
Nearest TSS
ENST00000502981/Upstream/439743; ENST00000509473/Downstream/205707;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2114362, chr4-CpG: 32/Downstream/205247
Upstream sequence
AAAAAGAAACTCCAAGCATGTACAAAATAAAGTAATAACTTTATTTTGGGAAGTGTAGGAGTTCACAAATTTGAATTGACCCTCAATTTTACTCATTATA
Downstream sequence
AATAACTAGGCTTCAAAACCCATCAAAGTTCCCATATGTAGCTTGTTTTCTACAAATTCTTTTTTCTATTTGGAACCACTTTAAAATTACTGACGTGCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate