Basic Information
VIS ID
TVIS44033715
Fusion event
HTLV-1-TREML2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
NCBI36/hg18
Start
41274211/41198495 (Hg38)
End
41274211/41198495 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
TREML2
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-135b-3p ; hsa-mir-6824-5p ; hsa-mir-6867-5p ; hsa-mir-6783-5p
Nearest miRNA
hsa-mir-1236/Upstream/2124114; hsa-mir-10398/Downstream/400228;
Nearest TSS
ENST00000381078/Upstream/35309; ENST00000448827/Downstream/2699;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/96891, chr6-CpG: 64/Downstream/173003
Upstream sequence
CTCACTTTTGTGTATACACTGTCAGCAGAGGGGCCTGTGGAGACAATACTTATTGAATAAGGTCTGGCAAGAGGAGAGGAAGAAGACATCATGAAAGTTG
Downstream sequence
AAGATCATGGTGAAGGGTAGAGTGGATATTGTCCTGCTGTCACAGAACCCACAGATTGAGGGGGAAATACAGCCCCGCCTTCAGGGAGCTTGCCCCAATC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate