Basic Information
VIS ID
TVIS44033744
Fusion event
HTLV-1-OLFM3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
NCBI36/hg18
Start
102063620/101825476 (Hg38)
End
102063620/101825476 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1E
Target gene
OLFM3
miRNAs that regulate target gene
hsa-mir-10b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1544168; hsa-mir-11399/Downstream/6071747;
Nearest TSS
ENST00000473358/Upstream/185890; ENST00000414923/Downstream/11553;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/588287, chr1-CpG: 85/Downstream/1699994
Upstream sequence
AGGTATTTTGTGAAAATTTAAGCGGTCATGTGATTATTACTAGTAAGTCCATTTATTTCAGCTTTTCCATATGAGAATCTTTCTTTAATGCTTAGTTTTC
Downstream sequence
TATAACAAATATATCCTTATCATAATTAGAAAAACTTCCTATGGTAGAAACTAGGACTATATACTATTTCATTTTCTGGTAACATTTTATATAGTGAACA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate