Basic Information
VIS ID
TVIS44033755
Fusion event
HTLV-1-ERCC6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
50385368/49507316 (Hg38)
End
50385368/49507316 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
ERCC6
miRNAs that regulate target gene
hsa-mir-4477a ; hsa-mir-126-5p
Nearest miRNA
hsa-mir-1265/Upstream/521729; hsa-mir-107/Downstream/1792257;
Nearest TSS
ENST00000439456/Upstream/836; ENST00000374115/Downstream/9798;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/108579, chr10-CpG: 68/Downstream/31272
Upstream sequence
aaatttcaactcttcaaggtaacaaaaggaagggctagctgaaatttacttgtgatcaacaagaactggttATCTGAAATTGCACTACACGGTAGTAAAG
Downstream sequence
GACCTATAAATAAGATCAATGAAGCACTGTTGGTCATTTCCAGAGAAGAACAGCAAATGGAAGAGGCAGTATATGGCCAAGTCTAAGGAAATAGCTATCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate