Basic Information
VIS ID
TVIS44033758
Fusion event
HTLV-1-MAST4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
66127948/66796364 (Hg38)
End
66127948/66796364 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAST4
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-324-3p
Nearest miRNA
hsa-mir-10397/Upstream/7092661; hsa-mir-103a-1/Downstream/5373103;
Nearest TSS
ENST00000502646/Upstream/7583; ENST00000470421/Downstream/32410;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/198653, chr5-CpG: 21/Downstream/207576
Upstream sequence
GGCATGTGAAGGGTATTGCGATTCGGTCTAAGAACGAGTGAAGAACTACATATTTGAGGGAGAAGTTTATTTTTCCTAAAATGAAATTCCACTCAGCGCA
Downstream sequence
GTCACTTAAAATGTCCCCATGTCTTAGTTTTTTTCTTCTTTTCATTTTGCAGAGGTTAAAAAATGTTCATTACCTTCTTTAGGTGTTGTCCTTCCTGGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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