Basic Information
VIS ID
TVIS44033764
Fusion event
HTLV-1-C22orf39 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
NCBI36/hg18
Start
17810701/19443178 (Hg38)
End
17810701/19443178 (Hg38)
Orient
-
Location type
Intronic
Target gene
C22orf39
miRNAs that regulate target gene
hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-508-5p ; hsa-mir-125a-3p ; hsa-mir-1914-3p ; hsa-mir-3158-3p ; hsa-mir-3184-5p ; hsa-mir-3665 ; hsa-mir-3908 ; hsa-mir-3942-5p ; hsa-mir-423-5p ; hsa-mir-4446-3p ; hsa-mir-4651 ; hsa-mir-4703-5p ; hsa-mir-4710 ; hsa-mir-4766-3p ; hsa-mir-5088-5p ; hsa-mir-5194 ; hsa-mir-541-3p ; hsa-mir-5697 ; hsa-mir-608 ; hsa-mir-621 ; hsa-mir-654-5p ; hsa-mir-657 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6782-5p
Nearest miRNA
hsa-mir-3198-1/Upstream/1462217; hsa-let-7a-3/Downstream/520575;
Nearest TSS
ENST00000624155/Upstream/10239; ENST00000431090/Downstream/4272;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/10464, chr22-CpG: 85/Downstream/4096
Upstream sequence
acccccacccccacccccacTGTTCACAGACACAGGGGCTCTTAGGGAGCACAGGAGAAAACACACTCAAGCAGGGAAATACTGTTCTTTAATGGACACC
Downstream sequence
CTTCTAACGTGATAGATTATTCTGCCCCAAAGAACAAATTAAAAGATATTCAACTTGCTGCCTGTGTCCAGGAAGAGAGCAGGGAGGGTGCTGGGCACAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate