Basic Information
VIS ID
TVIS44033777
Fusion event
HTLV-1-VGLL4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p25.2
Reference genome
NCBI36/hg18
Start
11662925/11646451 (Hg38)
End
11662925/11646451 (Hg38)
Orient
+
Location type
Intronic
Target gene
VGLL4
miRNAs that regulate target gene
hsa-mir-375 ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-222-3p ; hsa-mir-147b ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6809-5p ; hsa-mir-744-5p ; hsa-mir-4749-5p ; hsa-mir-6775-5p ; hsa-mir-4706 ; hsa-mir-5090 ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-194-3p ; hsa-mir-203a-3p ; hsa-mir-124-5p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-6499-3p ; hsa-mir-509-3p ; hsa-mir-1253 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-4756-3p ; hsa-mir-3163 ; hsa-mir-4255 ; hsa-mir-577 ; hsa-mir-5007-5p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-548av-3p ; hsa-mir-3662 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-6804-3p ; hsa-mir-4684-3p ; hsa-mir-455-3p ; hsa-mir-145-5p ; hsa-mir-5195-3p ; hsa-mir-6079 ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-4428 ; hsa-mir-4677-5p ; hsa-mir-22-5p ; hsa-mir-2116-5p ; hsa-mir-676-5p ; hsa-mir-3613-3p ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p
Nearest miRNA
hsa-mir-12127/Upstream/1251889; hsa-let-7g/Downstream/3849788;
Nearest TSS
ENST00000440867/Upstream/2527; ENST00000424884/Downstream/56583;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2995, chr3-CpG: 22/Downstream/58652
Upstream sequence
TCAATCAGAAAACTTTATCCATCATTGTCCCACATGGAAGAGAGGtggctgcacattagaaccaggggggagcttttaaaaatcttgctgctgaggttgc
Downstream sequence
atccccaactcatctgaggtgggaaccagcagcagtagcttctaaagtcccaggtgattccaatatgcagtcaaggttgagaaccattgCTTTCATCTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate