Basic Information
VIS ID
TVIS44033779
Fusion event
HTLV-1-ZFYVE9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
NCBI36/hg18
Start
52513063/52274803 (Hg38)
End
52513063/52274803 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1B
Target gene
ZFYVE9
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-222-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-580-5p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-1225-5p ; hsa-mir-1229-5p ; hsa-mir-4295 ; hsa-mir-4328 ; hsa-mir-3666 ; hsa-mir-5002-3p ; hsa-mir-141-5p ; hsa-mir-145-5p ; hsa-mir-5195-3p ; hsa-mir-4643 ; hsa-mir-526b-5p ; hsa-mir-591 ; hsa-mir-6758-5p ; hsa-mir-6856-5p ; hsa-mir-4684-3p ; hsa-mir-503-3p ; hsa-mir-367-5p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4755-3p ; hsa-mir-4753-5p ; hsa-mir-6768-3p
Nearest miRNA
hsa-mir-12136/Upstream/438401; hsa-mir-101-1/Downstream/1779276;
Nearest TSS
ENST00000473358/Upstream/58423; ENST00000469134/Downstream/21092;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/131971, chr1-CpG: 72/Downstream/90928
Upstream sequence
CCCCCAAAACTATGAAAATGGTTGTTGCTGTTATTATTTTAGAGTAGATGCTTATGTTTTTATATTATAATGTCATTTTCAGTTTTTGAATGGATATAAT
Downstream sequence
ATTACTTATAATGTAAATGTAGTTTATTAGCAGTTTTTAAAAATATTTCAAAGCACATAATATTCTGAAGGATTGCTTGTGGTTTAGGATGAACCCACTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate