Basic Information
VIS ID
TVIS44033802
Fusion event
HTLV-1-TDP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q32.11
Reference genome
NCBI36/hg18
Start
89514056/89977959 (Hg38)
End
89514056/89977959 (Hg38)
Orient
-
Location type
Intronic
Target gene
TDP1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-193b-3p ; hsa-mir-320a
Nearest miRNA
hsa-mir-1260a/Upstream/12711669; hsa-mir-1185-1/Downstream/3970267;
Nearest TSS
ENST00000550708/Upstream/2178; ENST00000556063/Downstream/7200;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/21710, chr14-CpG: 240/Downstream/82393
Upstream sequence
TTTTGGTTGGATGCCATGCAATCCCGTGGTCTGTCTCACAGTGTTTTAGAATGGGAAAGCTCTTTGGTTTCCTCTAGAGCTGGGAGCAGAGTTAATTCTT
Downstream sequence
ATGGCTCCAAGAATCGATAGAGGGGAAAGAGAAAGCCAAAGCAGCTGAATGTCAAATATCCAGATCCAGGTGGTGGCCAGTAGCAAACCACAGGATGGGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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