Basic Information
VIS ID
TVIS44033803
Fusion event
HTLV-1-TP63 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
NCBI36/hg18
Start
191022423/189821940 (Hg38)
End
191022423/189821940 (Hg38)
Orient
-
Location type
Intronic
Target gene
TP63
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-92a-3p ; hsa-mir-21-5p ; hsa-mir-124-3p ; hsa-mir-301b-3p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-4477b ; hsa-mir-1178-3p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428
Nearest miRNA
hsa-let-7g/Upstream/1133074; hsa-mir-3137/Downstream/7982;
Nearest TSS
ENST00000440867/Upstream/32139; ENST00000412203/Downstream/142181;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/874177, chr3-CpG: 99/Downstream/298351
Nearest cancer related gene
TP63(OG, No orient, 0)
Upstream sequence
AGCATATGATACTTACAGTATATCTTTTTTGGTTGTTTTATAAGATGAAGATTACAAATATGATATTTAGCACATCCTGGCTCTTCTTGAAAGCAGGGAC
Downstream sequence
TATGGCTCTTTTACTAAAGGACAAATAGTGCCTAAGgaaacaggagggtgtaggagaaagaattcagctttgtggtcagatagacctggggggttgaatt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate