Basic Information
VIS ID
TVIS44033806
Fusion event
HTLV-1-GPC6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
93454261/94004006 (Hg38)
End
93454261/94004006 (Hg38)
Orient
+
Location type
Intronic
Target gene
GPC6
miRNAs that regulate target gene
hsa-mir-361-5p ; hsa-mir-1279 ; hsa-mir-483-5p ; hsa-mir-32-3p ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-1297/Upstream/1513786; hsa-mir-1267/Downstream/2423223;
Nearest TSS
ENST00000623511/Upstream/167862; ENST00000617456/Downstream/183985;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/775382, chr13-CpG: 59/Downstream/545300
Upstream sequence
CTGAGAACCAATTGATTTCCCTTGGTAGATGTGTCATTCAAAAACTATATTTTACTGCTAATAGTACATAATCAAAGATACAGGCAAATTAATGAACTAC
Downstream sequence
TTTCTTACTAGAATAAAATAAAGTATGCTTAGGATCACCTTCTTCCATGTAACTTAGCATTTCATTGGCAAAATTGCATTAATCATTCCAGTACTTTCAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate