Basic Information
VIS ID
TVIS44033810
Fusion event
HTLV-1-BMF integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
NCBI36/hg18
Start
38178814/40099321 (Hg38)
End
38178814/40099321 (Hg38)
Orient
-
Location type
Intronic
Target gene
BMF
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-125b-5p ; hsa-mir-34c-5p ; hsa-mir-197-3p ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/3126420; hsa-mir-10393/Downstream/1592264;
Nearest TSS
ENST00000557528/Upstream/10489; ENST00000558715/Downstream/6765;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/59959, chr15-CpG: 44/Downstream/9335
Nearest cancer related gene
BMF(TSG, No orient, 0)
Upstream sequence
AAGTGTCAGGAAGCAATCAGGGGCTCCCTGAACAAAGGATCCAGTCTGCTAGGCAGAGAAGCTGCTAGTTAATAAACCATGCAAACACCAACTCGGGTAC
Downstream sequence
AACTTCCAAAAGAGCTCCCCAAATTACAAAGTCAGGTCCAAGCAAAATCCTAAAGTCATCTTTTAACATATTTCTAAAAGTACTCAACTGTCCCTGACTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate