Basic Information
VIS ID
TVIS44033834
Fusion event
HTLV-1-TSPAN12 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q31.31
Reference genome
NCBI36/hg18
Start
120231548/120804258 (Hg38)
End
120231548/120804258 (Hg38)
Orient
-
Location type
Intronic
Target gene
TSPAN12
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-4460 ; hsa-mir-4727-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-6718-5p ; hsa-mir-203b-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-5692a ; hsa-mir-140-5p
Nearest miRNA
hsa-mir-10525/Upstream/3783939; hsa-mir-10399/Downstream/6253830;
Nearest TSS
ENST00000635602/Upstream/51744; ENST00000445699/Downstream/34539;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/528827, chr7-CpG: 83/Downstream/52808
Upstream sequence
ACTAGGAAATTTGGTAGGTTTCAATTTACACATCTATACTTCTAACTATACTGTAGCCATCTGTTCTTTTAATGTCTAATAGTAAGTTATAGTATATTTG
Downstream sequence
AATATCCATAATATGTTTATATGTAATACTACCTCAGAAATATTAGTACTGTTTTCCGTTTTATGGAATAAGCAGGAGTTTGCCGCATTTATTAGTTGAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate