| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30029682 | HIV | ENSG00000149485.19 | protein_coding | FADS1 | No | No | 3992 | A0A0A0MR51 O60427 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FADS1 |
|---|---|
| DrugBank ID | DB00132 |
| Drug Name | alpha-Linolenic acid |
| Target ID | BE0000888 |
| UniProt ID | O60427 |
| Regulation Type | ligand |
| PubMed IDs | 16988497; 8673626; 11518758; 8487621; 10765977 |
| Citations | Xiang M, Rahman MA, Ai H, Li X, Harbige LS: Diet and gene expression: delta-5 and delta-6 desaturases in healthy Chinese and European subjects. Ann Nutr Metab. 2006;50(6):492-8. Epub 2006 Sep 19.@@Descomps B, Rodriguez A: [Essential fatty acids and prematurity: a triple experimental approach]. C R Seances Soc Biol Fil. 1995;189(5):781-96.@@Hoffman DR, DeMar JC, Heird WC, Birch DG, Anderson RE: Impaired synthesis of DHA in patients with X-linked retinitis pigmentosa. J Lipid Res. 2001 Sep;42(9):1395-401.@@Maniongui C, Blond JP, Ulmann L, Durand G, Poisson JP, Bezard J: Age-related changes in delta 6 and delta 5 desaturase activities in rat liver microsomes. Lipids. 1993 Apr;28(4):291-7.@@Mohan IK, Das UN: Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids. 2000 Jan;62(1):35-46. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Lineolic acids and derivatives |
| SMILES | CCC=C/CC=C/CC=C/CCCCCCCC(O)=O |
| Pathways | Alpha Linolenic Acid and Linoleic Acid Metabolism |
| PharmGKB | PA449384 |
| ChEMBL | CHEMBL8739 |
