| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10010617 | HBV | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS10042440 | HBV | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS20051410 | HPV | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS20040748 | HPV | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS20033782 | HPV | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS44026918 | HTLV-1 | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS44010555 | HTLV-1 | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
| TVIS44017582 | HTLV-1 | ENSG00000189403.15 | protein_coding | HMGB1 | No | No | 3146 | P09429 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HMGB1 |
|---|---|
| DrugBank ID | DB00608 |
| Drug Name | Chloroquine |
| Target ID | BE0003428 |
| UniProt ID | P09429 |
| Regulation Type | inhibitor |
| PubMed IDs | 23707973 |
| Citations | Yang M, Cao L, Xie M, Yu Y, Kang R, Yang L, Zhao M, Tang D: Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis. Biochem Pharmacol. 2013 Aug 1;86(3):410-8. doi: 10.1016/j.bcp.2013.05.013. Epub 2013 May 22. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | 4-aminoquinolines |
| SMILES | CCN(CC)CCCC(C)NC1=CC=NC2=CC(Cl)=CC=C12 |
| Pathways | |
| PharmGKB | PA448948 |
| ChEMBL | CHEMBL76 |
