| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30069936 | HIV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS30069937 | HIV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS30069938 | HIV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS20045044 | HPV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS20062858 | HPV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS20062392 | HPV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS20062508 | HPV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS20047015 | HPV | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS44016880 | HTLV-1 | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
| TVIS44046016 | HTLV-1 | ENSG00000184156.18 | protein_coding | KCNQ3 | No | No | 3786 | O43525 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNQ3 |
|---|---|
| DrugBank ID | DB00321 |
| Drug Name | Amitriptyline |
| Target ID | BE0002398 |
| UniProt ID | O43525 |
| Regulation Type | inhibitor |
| PubMed IDs | 17456683; 26627826 |
| Citations | Punke MA, Friederich P: Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels. Anesth Analg. 2007 May;104(5):1256-64, tables of contents.@@Syeda R, Santos JS, Montal M: The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine. J Biol Chem. 2016 Feb 5;291(6):2931-7. doi: 10.1074/jbc.M115.683185. Epub 2015 Dec 1. |
| Groups | Approved |
| Direct Classification | Dibenzocycloheptenes |
| SMILES | CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA448385 |
| ChEMBL | CHEMBL629 |
