| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10010882 | HBV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS30067833 | HIV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS20012857 | HPV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS20062294 | HPV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS20023366 | HPV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS20022730 | HPV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS20061784 | HPV | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS44016703 | HTLV-1 | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
| TVIS44049057 | HTLV-1 | ENSG00000105976.16 | protein_coding | MET | Yes | No | 4233 | E6Y365 P08581 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MET |
|---|---|
| DrugBank ID | DB08865 |
| Drug Name | Crizotinib |
| Target ID | BE0000915 |
| UniProt ID | P08581 |
| Regulation Type | inhibitor |
| PubMed IDs | 22594847; 10592235 |
| Citations | Forde PM, Rudin CM: Crizotinib in the treatment of non-small-cell lung cancer. Expert Opin Pharmacother. 2012 Jun;13(8):1195-201. doi: 10.1517/14656566.2012.688029.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Investigational |
| Direct Classification | Pyrazolylpyridines |
| SMILES | C[C@@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl |
| Pathways | |
| PharmGKB | PA165946122 |
| ChEMBL | CHEMBL601719 |
