| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046482 | HBV | ENSG00000010671.18 | protein_coding | BTK | Yes | No | 695 | Q06187 Q5JY90 |
| TVIS10057601 | HBV | ENSG00000010671.18 | protein_coding | BTK | Yes | No | 695 | Q06187 Q5JY90 |
| TVIS30021024 | HIV | ENSG00000010671.18 | protein_coding | BTK | Yes | No | 695 | Q06187 Q5JY90 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BTK |
|---|---|
| DrugBank ID | DB15227 |
| Drug Name | Tirabrutinib |
| Target ID | BE0001284 |
| UniProt ID | Q06187 |
| Regulation Type | inhibitor |
| PubMed IDs | 33275726; 33689480 |
| Citations | Castillo JJ, Treon SP: Management of Waldenstrom macroglobulinemia in 2020. Hematology Am Soc Hematol Educ Program. 2020 Dec 4;2020(1):372-379. doi: 10.1182/hematology.2020000121.@@Zheng TJ, Lofurno ER, Melrose AR, Lakshmanan HHS, Pang J, Phillips KG, Fallon ME, Kohs TCL, Ngo ATP, Shatzel JJ, Hinds MT, McCarty OJT, Aslan JE: Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function. Am J Physiol Cell Physiol. 2021 May 1;320(5):C902-C915. doi: 10.1152/ajpcell.00296.2020. Epub 2021 Mar 10. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | CC#CC(=O)N1CC[C@H](C1)N1C(=O)N(C2=C(N)N=CN=C12)C1=CC=C(OC2=CC=CC=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4071161 |
