Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10036438HBVENSG00000120251.22protein_codingGRIA2NoNo2891P42262
TVIS10042391HBVENSG00000120251.22protein_codingGRIA2NoNo2891P42262
TVIS30061405HIVENSG00000120251.22protein_codingGRIA2NoNo2891P42262
TVIS20002300HPVENSG00000120251.22protein_codingGRIA2NoNo2891P42262
TVIS20058835HPVENSG00000120251.22protein_codingGRIA2NoNo2891P42262
TCGA Plot Options
Drug Information
GeneGRIA2
DrugBank IDDB01174
Drug NamePhenobarbital
Target IDBE0000829
UniProt IDP42262
Regulation Typeantagonist
PubMed IDs11264449; 10487207; 20051697
CitationsYamakura T, Bertaccini E, Trudell JR, Harris RA: Anesthetics and ion channels: molecular models and sites of action. Annu Rev Pharmacol Toxicol. 2001;41:23-51.@@Krasowski MD, Harrison NL: General anaesthetic actions on ligand-gated ion channels. Cell Mol Life Sci. 1999 Aug 15;55(10):1278-303.@@Jin LJ, Schlesinger F, Song YP, Dengler R, Krampfl K: The interaction of the neuroprotective compounds riluzole and phenobarbital with AMPA-type glutamate receptors: a patch-clamp study. Pharmacology. 2010;85(1):54-62. doi: 10.1159/000268641. Epub 2009 Dec 23.
GroupsApproved; Investigational
Direct ClassificationBarbituric acid derivatives
SMILESCCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1
Pathways
PharmGKBPA450911
ChEMBLCHEMBL40