| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30008124 | HIV | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
| TVIS44031350 | HTLV-1 | ENSG00000128271.22 | protein_coding | ADORA2A | No | No | 135 | P29274 X5DNB4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADORA2A |
|---|---|
| DrugBank ID | DB11757 |
| Drug Name | Istradefylline |
| Target ID | BE0000924 |
| UniProt ID | P29274 |
| Regulation Type | antagonist |
| PubMed IDs | 28881378; 23700273 |
| Citations | Mukai M, Uchimura T, Zhang X, Greene D, Vergeire M, Cantillon M: Effects of Rifampin on the Pharmacokinetics of a Single Dose of Istradefylline in Healthy Subjects. J Clin Pharmacol. 2018 Feb;58(2):193-201. doi: 10.1002/jcph.1003. Epub 2017 Sep 7.@@Dungo R, Deeks ED: Istradefylline: first global approval. Drugs. 2013 Jun;73(8):875-82. doi: 10.1007/s40265-013-0066-7. |
| Groups | Approved; Investigational |
| Direct Classification | Xanthines |
| SMILES | [H]C(=C([H])C1=CC(OC)=C(OC)C=C1)C1=NC2=C(N1C)C(=O)N(CC)C(=O)N2CC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL431770 |
